Drug-free in vitro activation combined with ADSCs-derived exosomes restores ovarian function of rats with premature ovarian insufficiency

• Main Authors: Qian Li (Author), Zhiqiang Zhang (Author), Wenxin Shi (Author), Zhongkang Li (Author), Yanlai Xiao (Author), Jingkun Zhang (Author), Xianghua Huang (Author)
• Format: Book
• Published: BMC, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Drug-free in vitro activation (IVA) is a new protocol to activate residual dormant follicles for fertility restoration in patients with premature ovarian insufficiency (POI). However, several deficiencies have reduced its clinical efficacy rate. Our previous studies have confirme...