A Single H1 Promoter Can Drive Both Guide RNA and Endonuclease Expression in the CRISPR-Cas9 System

The RNA-guided endonuclease Cas9 (CRISPR-Cas9) genome editing system has been widely used for biomedical research and holds great potential for therapeutic applications in eukaryotes. The conventional vector-based CRISPR-Cas9 delivery system requires two different RNA polymerase promoters for expres...

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Bibliographic Details
Main Authors: Zongliang Gao (Author), Elena Herrera-Carrillo (Author), Ben Berkhout (Author)
Format: Book
Published: Elsevier, 2019-03-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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