Time-Prolonged Release of Tumor-Targeted Protein-MMAE Nanoconjugates from Implantable Hybrid Materials

• Main Authors: Naroa Serna (Author), Aïda Falgàs (Author), Annabel García-León (Author), Ugutz Unzueta (Author), Yáiza Núñez (Author), Alejandro Sánchez-Chardi (Author), Carlos Martínez-Torró (Author), Ramón Mangues (Author), Esther Vazquez (Author), Isolda Casanova (Author), Antonio Villaverde (Author)
• Format: Book
• Published: MDPI AG, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The sustained release of small, tumor-targeted cytotoxic drugs is an unmet need in cancer therapies, which usually rely on punctual administration regimens of non-targeted drugs. Here, we have developed a novel concept of protein-drug nanoconjugates, which are packaged as slow-releasing chemically h...