Hantaan Virus Infection Induces CXCL10 Expression through TLR3, RIG-I, and MDA-5 Pathways Correlated with the Disease Severity

• Main Authors: Yusi Zhang (Author), Bei Liu (Author), Ying Ma (Author), Jing Yi (Author), Chunmei Zhang (Author), Yun Zhang (Author), Zhuwei Xu (Author), Jiuping Wang (Author), Kun Yang (Author), Angang Yang (Author), Ran Zhuang (Author), Boquan Jin (Author)
• Format: Book
• Published: Hindawi Limited, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hantaan virus (HTNV) is a major agent causing hemorrhagic fever with renal syndrome (HFRS). Although the pathogenesis of HFRS is unclear, some reports have suggested that the abundant production of proinflammatory cytokines and uncontrolled inflammatory responses may contribute to the development of...