Hantaan Virus Infection Induces CXCL10 Expression through TLR3, RIG-I, and MDA-5 Pathways Correlated with the Disease Severity

• Главные авторы: Yusi Zhang (Автор), Bei Liu (Автор), Ying Ma (Автор), Jing Yi (Автор), Chunmei Zhang (Автор), Yun Zhang (Автор), Zhuwei Xu (Автор), Jiuping Wang (Автор), Kun Yang (Автор), Angang Yang (Автор), Ran Zhuang (Автор), Boquan Jin (Автор)
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• Опубликовано: Hindawi Limited, 2014-01-01T00:00:00Z.
• Предметы: article
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Hantaan virus (HTNV) is a major agent causing hemorrhagic fever with renal syndrome (HFRS). Although the pathogenesis of HFRS is unclear, some reports have suggested that the abundant production of proinflammatory cytokines and uncontrolled inflammatory responses may contribute to the development of...