Clofibrate improves myocardial ischemia-induced damage through regulation of renin-angiotensin system and favours a pro-vasodilator profile in left ventricle

• Main Authors: L. Ibarra-Lara (Author), M. Sánchez-Aguilar (Author), L. Del Valle-Mondragón (Author), E. Soria-Castro (Author), L.G. Cervantes-Pérez (Author), G. Pastelín-Hernández (Author), A. Sánchez-Mendoza (Author)
• Format: Book
• Published: Elsevier, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Myocardial ischemia initiates a chain of pathological conditions leading to cardiomyocyte death. Therefore, pharmacological treatment to stop ischemia-induced damage is necessary. Fibrates, have been reported to decrease inflammatory markers and to modulate the renin-angiotensin system (RAS). Our ai...