Enhancing the dissolution of phenylbutazone using Syloid® based mesoporous silicas for oral equine applications

Enhancing the dissolution of phenylbutazone using Syloid® based mesoporous silicas for oral equine applications

Three mesoporous silica excipients (Syloid® silicas AL-1 FP, XDP 3050 and XDP 3150) were formulated with a model drug known for its poor aqueous solubility, namely phenylbutazone, in an attempt to enhance the extent and rate of drug dissolution. Although other forms of mesoporous silica have been in...

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Main Authors: Laura J. Waters (Author), John P. Hanrahan (Author), Joseph M. Tobin (Author), Catherine V. Finch (Author), Gareth M.B. Parkes (Author), Shamsuddeen A. Ahmad (Author), Faraj Mohammad (Author), Maria Saleem (Author)
Format: Book
Published: Elsevier, 2018-06-01T00:00:00Z.
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