Effect of Oxygen and Water on the Stability of Imipenem and Cilastatin Sodium for Injection

• Главные авторы: Meng Zhang (Автор), Chun-Feng Liu (Автор), Xiao-Yan Chen (Автор), Li-Na Yang (Автор), Chun-Mei Zhu (Автор), Jian-Hao Teng (Автор), Hao-Xiang Wu (Автор), Fu-Li Zhang (Автор)
• Формат: ‌
• Опубликовано: Georg Thieme Verlag KG, 2022-06-01T00:00:00Z.
• Предметы: article
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The study aimed to investigate the factors affecting the stability of imipenem and cilastatin sodium for injection (IMI/CIL) to improve the quality and stability in IMI/CIL preparation. In this study, the effects of headspace oxygen (HO), water content, particle shape, and particle size on the stabi...