Association Between the P2RY12 Receptor Gene Polymorphism and Aspirin Resistance in Patients with Coronary Artery Disease

• 主要な著者: Ludmila Karazhanova (著者), Sholpan Zhukusheva (著者), Ainur Akilzhanova (著者)
• フォーマット: 図書
• 出版事項: University Library System, University of Pittsburgh, 2014-12-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Introduction. Platelet activation and aggregation are key elements in the development of coronary atherosclerosis. Recent studies have shown that the two polymorphisms of platelet ADP receptor P2RY12 (haplotypes H2 and 34T) are associated with increased platelet aggregation and atherothrombotic risk...