The pharmacokinetics of oral trazpiroben (TAK‐906) after organic anion transporting polypeptide 1B1/1B3 inhibition: A phase I, randomized study

Abstract Trazpiroben is a dopamine D2/D3 receptor antagonist under development for the treatment of gastroparesis. This phase I, open‐label, randomized, two‐way crossover study (NCT04121078) evaluated the effect of single‐dose intravenous rifampin, a potent inhibitor of the organic anion transportin...

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Main Authors: Jatinder K. Mukker (Author), George Dukes (Author), Max Tolkoff (Author), Lisi Wang (Author), Cristina Almansa (Author), Susanna Y. Huh (Author), Mitsuhiro Nishihara (Author), Diane Ramsden (Author), Chunlin Chen (Author)
Format: Book
Published: Wiley, 2022-06-01T00:00:00Z.
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