Hypothermia Reduces Toll-Like Receptor 3-Activated Microglial Interferon-β and Nitric Oxide Production

• Prif Awduron: Tomohiro Matsui (Awdur), Yukari Motoki (Awdur), Yusuke Yoshida (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Hindawi Limited, 2013-01-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Therapeutic hypothermia protects neurons after injury to the central nervous system (CNS). Microglia express toll-like receptors (TLRs) that play significant roles in the pathogenesis of sterile CNS injury. To elucidate the possible mechanisms involved in the neuroprotective effect of therapeutic hy...