Protection against Amyloid-β Oligomer Neurotoxicity by Small Molecules with Antioxidative Properties: Potential for the Prevention of Alzheimer's Disease Dementia

• मुख्य लेखकों: Wataru Araki (लेखक), Fuyuki Kametani (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2022-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Soluble oligomeric assemblies of amyloid β-protein (Aβ), called Aβ oligomers (AβOs), have been recognized as primary pathogenetic factors in the molecular pathology of Alzheimer's disease (AD). AβOs exert neurotoxicity and synaptotoxicity and play a critical role in the pathological progression...