Effect of the Phosphodiesterase 5 Inhibitor Sildenafil on Ischemia-Reperfusion-Induced Muscle Mitochondrial Dysfunction and Oxidative Stress

• Príomhchruthaitheoirí: Liliane Tetsi (Údar), Anne-Laure Charles (Údar), Isabelle Georg (Údar), Fabienne Goupilleau (Údar), Anne Lejay (Údar), Samy Talha (Údar), Myriam Maumy-Bertrand (Údar), Claire Lugnier (Údar), Bernard Geny (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: MDPI AG, 2019-04-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

Lower-limb ischemia-reperfusion (IR) is frequent and associated with significant morbidity and mortality. Phosphodiesterase 5 inhibitors demonstrated antioxidant and beneficial effects in several organs submitted to IR, but their effects on muscle mitochondrial functions after lower-limb IR are unkn...