Mitoferrin-1 Promotes Proliferation and Abrogates Protein Oxidation via the Glutathione Pathway in Glioblastoma

• Egile Nagusiak: Md Yousuf Ali (Egilea), Corinne E. Griguer (Egilea), Susanne Flor (Egilea), Claudia R. Oliva (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2023-02-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Median overall survival is very low in patients with glioblastoma (GBM), largely because these tumors become resistant to therapy. Recently, we found that a decrease in the cytosolic labile iron pool underlies the acquisition of radioresistance. Both cytosolic and mitochondrial iron are important fo...