Mitoferrin-1 Promotes Proliferation and Abrogates Protein Oxidation via the Glutathione Pathway in Glioblastoma

• Hauptverfasser: Md Yousuf Ali (Verfasst von), Corinne E. Griguer (Verfasst von), Susanne Flor (Verfasst von), Claudia R. Oliva (Verfasst von)
• Format: Buch
• Veröffentlicht: MDPI AG, 2023-02-01T00:00:00Z.
• Schlagworte: article
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Median overall survival is very low in patients with glioblastoma (GBM), largely because these tumors become resistant to therapy. Recently, we found that a decrease in the cytosolic labile iron pool underlies the acquisition of radioresistance. Both cytosolic and mitochondrial iron are important fo...