Exploring new Horizons in overcoming P-glycoprotein-mediated multidrug-resistant breast cancer via nanoscale drug delivery platforms

• Main Authors: Paras Famta (Author), Saurabh Shah (Author), Essha Chatterjee (Author), Hoshiyar Singh (Author), Biswajit Dey (Author), Santosh Kumar Guru (Author), Shashi Bala Singh (Author), Saurabh Srivastava (Author)
• Format: Book
• Published: Elsevier, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The high probability (13%) of women developing breast cancer in their lifetimes in America is exacerbated by the emergence of multidrug resistance after exposure to first-line chemotherapeutic agents. Permeation glycoprotein (P-gp)-mediated drug efflux is widely recognized as the major driver of thi...