SUMOtherapeutics for Ischemic Stroke

• Main Authors: Paramesh Karandikar (Author), Jakob V. E. Gerstl (Author), Ari D. Kappel (Author), Sae-Yeon Won (Author), Daniel Dubinski (Author), Monica Emili Garcia-Segura (Author), Florian A. Gessler (Author), Alfred Pokmeng See (Author), Luca Peruzzotti-Jametti (Author), Joshua D. Bernstock (Author)
• Format: Book
• Published: MDPI AG, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The small, ubiquitin-like modifier (SUMO) is a post-translational modifier with a profound influence on several key biological processes, including the mammalian stress response. Of particular interest are its neuroprotective effects, first recognized in the 13-lined ground squirrel (<i>Ictido...