FGF21 resistance is not mediated by downregulation of beta-klotho expression in white adipose tissue

• Asıl Yazarlar: Kathleen R. Markan (Yazar), Meghan C. Naber (Yazar), Sarah M. Small (Yazar), Lila Peltekian (Yazar), Rachel L. Kessler (Yazar), Matthew J. Potthoff (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2017-06-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Objective: Fibroblast growth factor 21 (FGF21) is an endocrine hormone that regulates metabolic homeostasis. Previous work has suggested that impairment of FGF21 signaling in adipose tissue may occur through downregulation of the obligate FGF21 co-receptor, β-klotho, which leads to "FGF21 resis...