β1-Adrenergic Receptor Gene Polymorphisms and the Acute Response to Atenolol in Healthy Young Japanese Subjects

• Główni autorzy: Toshiyuki Sasaguri (Autor), Fumie Shiraishi (Autor), Tatsuya Yoshihara (Autor), Fumi Takahashi-Yanaga (Autor), Sachio Morimoto (Autor)
• Format: Książka
• Wydane: Elsevier, 2011-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Polymorphisms at codons 49 and 389 of the β1-adrenergic receptor gene have been shown to alter the receptor function in vitro, whereas it remains controversial whether they influence the response to β-blocker in vivo. In the present study, we investigated whether these polymorphisms influence the ac...