Gankyrin gene deletion followed by proteomic analysis: insight into the roles of Gankyrin in Tumorigenesis and Metastasis

• Main Authors: Luo Xue (Author), Chen Liang (Author), Dai Jiang (Author), Gao Yanfei (Author), Wang Hongli (Author), Wang Na (Author), Zhao Yongqiang (Author), Liu Feng (Author), Sang Zhihong (Author), Wang Jie (Author), Li Weihua (Author), He Kun (Author), Jin Baofeng (Author), Man Jianghong (Author), Zhang Wei (Author), Xia Qing (Author)
• Format: Book
• Published: BMC, 2012-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Gankyrin was originally purified and characterized as the p28 component of the 26S proteasome, and later identified as an oncogenic protein in hepatocellular carcinomas (HCC). It has recently been found to be highly expressed in seve...