Is BDNF sufficient for information transfer between microglia and dorsal horn neurons during the onset of central sensitization?

• Main Authors: Balasubramanyan Sridhar (Author), Stebbing Martin J (Author), Lu Van B (Author), Biggs James E (Author), Smith Peter A (Author)
• Format: Book
• Published: SAGE Publishing, 2010-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Peripheral nerve injury activates spinal microglia. This leads to enduring changes in the properties of dorsal horn neurons that initiate central sensitization and the onset of neuropathic pain. Although a variety of neuropeptides, cytokines, chemokines and neuro...