CO2 permeability of the rat erythrocyte membrane and its inhibition

• Main Authors: Samer Al-Samir (Author), Maximilian Prill (Author), Claudiu T. Supuran (Author), Gerolf Gros (Author), Volker Endeward (Author)
• Formato: Libro
• Publicado: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

We have studied the CO2 permeability of the erythrocyte membrane of the rat using a mass spectrometric method that employs 18 O-labelled CO2. The method yields, in addition, the intraerythrocytic carbonic anhydrase activity and the membrane HCO3− permeability. For normal rat erythrocytes, we find at...