Methylglyoxal Inhibits Smooth Muscle Contraction in Isolated Blood Vessels

• Main Authors: Masashi Mukohda (Author), Hideyuki Yamawaki (Author), Hidemi Nomura (Author), Muneyoshi Okada (Author), Yukio Hara (Author)
• Format: Book
• Published: Elsevier, 2009-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Methylglyoxal (MGO) is a metabolite of glucose. In addition to evidence that increased plasma MGO level is associated with diabetic vascular complications, recent studies demonstrated that MGO accumulated in vascular tissues of hypertensive animals. We hypothesized that MGO could directly affect vas...