The Role of Uptake and Efflux Transporters in the Disposition of Glucuronide and Sulfate Conjugates

• 主要な著者: Erkka Järvinen (著者), Feng Deng (著者), Wilma Kiander (著者), Alli Sinokki (著者), Heidi Kidron (著者), Noora Sjöstedt (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2022-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Glucuronidation and sulfation are the most typical phase II metabolic reactions of drugs. The resulting glucuronide and sulfate conjugates are generally considered inactive and safe. They may, however, be the most prominent drug-related material in the circulation and excreta of humans. The glucuron...