Pharmacokinetic behavior of phenytoin in head trauma and cerebrovascular accident patients in an iranian population

• Main Authors: Shahnaz Alimardani (Author), Sima Sadrai (Author), Hamidreza Taghvaye Masoumi (Author), Pooneh Salari (Author), Atabak Najafi (Author), Behzad Eftekhar (Author), Mojtaba Mojtahedzadeh (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Acute brain injury is one of the leading causes of morbidity and mortality worldwide. Phenytoin has been commonly used as an anticonvulsant agent for the treatment or prophylaxis of seizures following acute brain injury. After a severe head injury, several pharmacokinetic changes occur. T...