Simultaneous determination of asenapine and valproic acid in human plasma using LCâMS/MS: Application of the method to support pharmacokinetic study

• मुख्य लेखकों: Ambavaram Vijaya Bhaskar Reddy (लेखक), Nandigam Venugopal (लेखक), Gajulapalle Madhavi (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2013-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Combination of asenapine with valproic acid received regulatory approval for acute treatment of schizophrenia and maniac episodes of bipolar disorders. A simple LCâMS/MS method was developed and validated for simultaneous quantification of asenapine and valproic acid in human plasma. Internal standa...