Preclinical models of idiosyncratic drug-induced liver injury (iDILI): Moving towards prediction

• المؤلفون الرئيسيون: Antonio Segovia-Zafra (مؤلف), Daniel E. Di Zeo-Sánchez (مؤلف), Carlos López-Gómez (مؤلف), Zeus Pérez-Valdés (مؤلف), Eduardo García-Fuentes (مؤلف), Raúl J. Andrade (مؤلف), M. Isabel Lucena (مؤلف), Marina Villanueva-Paz (مؤلف)
• التنسيق: كتاب
• منشور في: Elsevier, 2021-12-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Idiosyncratic drug-induced liver injury (iDILI) encompasses the unexpected harms that prescription and non-prescription drugs, herbal and dietary supplements can cause to the liver. iDILI remains a major public health problem and a major cause of drug attrition. Given the lack of biomarkers for iDIL...