The role of Sertoli cell-derived miR-143-3p in male fertility declines with age

• Main Authors: Jinlian Liang (Author), Jiaxin Mei (Author), Derong Chen (Author), Ziyan Xiao (Author), Meirong Hu (Author), Siying Wei (Author), Zhaoyang Wang (Author), Rufei Huang (Author), Lu Li (Author), Tao Ye (Author), Jingxian Deng (Author), Yuan Liu (Author), Yuxin Wang (Author), Lei Zhang (Author), Yan Yang (Author), Yadong Huang (Author)
• Format: Book
• Published: Elsevier, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

As delayed parenthood becomes more prevalent, understanding age-related testosterone decline and its impact on male fertility has gained importance. However, molecular mechanisms concerning testicular aging remain largely undiscovered. Our study highlights that miR-143-3p, present in aging Sertoli c...