The Ras/ERK signaling pathway couples antimicrobial peptides to mediate resistance to dengue virus in Aedes mosquitoes.

Aedes mosquitoes can transmit dengue and several other severe vector-borne viral diseases, thereby influencing millions of people worldwide. Insects primarily control and clear the viral infections via their innate immune systems. Mitogen-Activated Protein Kinases (MAPKs) and antimicrobial peptides...

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Main Authors: Wen-Quan Liu (Author), Si-Qi Chen (Author), Hao-Qiang Bai (Author), Qi-Mei Wei (Author), Sheng-Nan Zhang (Author), Chen Chen (Author), Yi-Han Zhu (Author), Tang-Wei Yi (Author), Xiao-Pu Guo (Author), Si-Yuan Chen (Author), Meng-Jie Yin (Author), Chen-Feng Sun (Author), Shao-Hui Liang (Author)
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Published: Public Library of Science (PLoS), 2020-08-01T00:00:00Z.
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