A novel Mutein of TNFα Containing the Arg-Gly-Asp Sequence Shows Reduced Toxicity in Intestine

The effects of human tumour necrosis factor-α (TNFα), or its mutein (F4168) having the cell adhesive Arg-Gly-Asp sequence at the N-terminus, on intestinal injury, were examined. Histopathological examination revealed that an intravenous injection of TNFα resulted in marked haemorrhage or oedema in t...

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Bibliographic Details
Main Authors: H. Shikama (Author), K. Miyata (Author), N. Sakae (Author), K. Kuroda (Author), K. Nishimura (Author), S. Yotsuya (Author), M. Kato (Author)
Format: Book
Published: Hindawi Limited, 1994-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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