A novel Mutein of TNFα Containing the Arg-Gly-Asp Sequence Shows Reduced Toxicity in Intestine
The effects of human tumour necrosis factor-α (TNFα), or its mutein (F4168) having the cell adhesive Arg-Gly-Asp sequence at the N-terminus, on intestinal injury, were examined. Histopathological examination revealed that an intravenous injection of TNFα resulted in marked haemorrhage or oedema in t...
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Main Authors: | , , , , , , |
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Format: | Book |
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Hindawi Limited,
1994-01-01T00:00:00Z.
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A1234.567 |
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Copy 1 | Available |