Colitis Is Effectively Ameliorated by (±)-8-Acetonyl-dihydrocoptisine via the XBP1-NF-κB Pathway

• Main Authors: HaiJing Zhang (Author), GuangMing Song (Author), ZhiHui Zhang (Author), HuaChen Song (Author), XiaoNan Tang (Author), AnJun Deng (Author), WenJie Wang (Author), LianQiu Wu (Author), HaiLin Qin (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ulcerative colitis (UC) is a recurrent, chronic intestinal disease. Available treatments for UC are poor effective and/or cause severe adverse events. X-box binding protein 1 (XBP1) and nuclear factor-κB (NF-κB) have been reported to play important roles in UC. Specifically, deletion or downregulati...