Colitis Is Effectively Ameliorated by (±)-8-Acetonyl-dihydrocoptisine via the XBP1-NF-κB Pathway

• Auteurs principaux: HaiJing Zhang (Auteur), GuangMing Song (Auteur), ZhiHui Zhang (Auteur), HuaChen Song (Auteur), XiaoNan Tang (Auteur), AnJun Deng (Auteur), WenJie Wang (Auteur), LianQiu Wu (Auteur), HaiLin Qin (Auteur)
• Format: Livre
• Publié: Frontiers Media S.A., 2017-09-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Ulcerative colitis (UC) is a recurrent, chronic intestinal disease. Available treatments for UC are poor effective and/or cause severe adverse events. X-box binding protein 1 (XBP1) and nuclear factor-κB (NF-κB) have been reported to play important roles in UC. Specifically, deletion or downregulati...