Increased Epithelial Expression of CTGF and S100A7 with Elevated Subepithelial Expression of IL-1β in Trachomatous Trichiasis.

• Main Authors: Tamsyn Derrick (Author), Philip J Luthert (Author), Hodan Jama (Author), Victor H Hu (Author), Patrick Massae (Author), David Essex (Author), Martin J Holland (Author), Matthew J Burton (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

PURPOSE:To characterize the histological appearance and expression of pro-inflammatory mediators, growth factors, matrix metalloproteinases and biomarkers of epithelial-mesenchymal transition (EMT) in healthy control and trachomatous trichiasis (TT) conjunctival tissue. METHODS:Conjunctival biopsies...