Isorhynchophylline inhibits inflammatory responses in endothelial cells and macrophages through the NF-κB/NLRP3 signaling pathway

• Main Authors: Li-Hua Wang (Author), Zheng-Wei Gu (Author), Jie Li (Author), Wen-Qing Yang (Author), Yun-Lun Li (Author), Dong-Mei Qi (Author), Dan-Yang Wang (Author), Hai-Qiang Jiang (Author)
• Format: Book
• Published: BMC, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Atherosclerosis is a chronic inflammatory disease of arterial wall, which is closely related to inflammatory reaction. In this study, the anti-inflammatory effect of isorhynchophylline was studied by NF- κB / NLRP3 pathway. Methods (1) ApoE−/− mice were fed with high-fat diet to...