Isorhynchophylline inhibits inflammatory responses in endothelial cells and macrophages through the NF-κB/NLRP3 signaling pathway

• Autori principali: Li-Hua Wang (Autore), Zheng-Wei Gu (Autore), Jie Li (Autore), Wen-Qing Yang (Autore), Yun-Lun Li (Autore), Dong-Mei Qi (Autore), Dan-Yang Wang (Autore), Hai-Qiang Jiang (Autore)
• Natura: Libro
• Pubblicazione: BMC, 2023-03-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Abstract Background Atherosclerosis is a chronic inflammatory disease of arterial wall, which is closely related to inflammatory reaction. In this study, the anti-inflammatory effect of isorhynchophylline was studied by NF- κB / NLRP3 pathway. Methods (1) ApoE−/− mice were fed with high-fat diet to...