Isorhynchophylline inhibits inflammatory responses in endothelial cells and macrophages through the NF-κB/NLRP3 signaling pathway

• 主要な著者: Li-Hua Wang (著者), Zheng-Wei Gu (著者), Jie Li (著者), Wen-Qing Yang (著者), Yun-Lun Li (著者), Dong-Mei Qi (著者), Dan-Yang Wang (著者), Hai-Qiang Jiang (著者)
• フォーマット: 図書
• 出版事項: BMC, 2023-03-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Abstract Background Atherosclerosis is a chronic inflammatory disease of arterial wall, which is closely related to inflammatory reaction. In this study, the anti-inflammatory effect of isorhynchophylline was studied by NF- κB / NLRP3 pathway. Methods (1) ApoE−/− mice were fed with high-fat diet to...