GM-CSF-miRNA-Jak2/Stat3 Signaling Mediates Chemotherapy-Induced Cancer Cell Stemness in Gastric Cancer

• Main Authors: Xue Xiang (Author), Hai-zhong Ma (Author), Ya-qiong Chen (Author), Dong-zhi Zhang (Author), Shi-xu Ma (Author), Hong-jing Wang (Author), De-ming Liu (Author), Yuan Yuan (Author), Hui Cai (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chemotherapy serves as the first choice in clinic to treat advanced gastric cancer. However, emerging evidence indicated the induction of drug resistance and cancer stem cells occasionally by chemotherapy, which seriously limit the therapeutic effects, but the regulatory mechanism remains unclear. H...