A Polymorphism of ORAI1 rs7135617, Is Associated with Susceptibility to Rheumatoid Arthritis

• Main Authors: Jeng-Hsien Yen (Author), Che-Mai Chang (Author), Yu-Wen Hsu (Author), Chih-Hung Lee (Author), Mei-Shin Wu (Author), Daw-Yang Hwang (Author), Ben-Kuen Chen (Author), Hsien-Tzung Liao (Author), Man-Tzu Marcie Wu (Author), Wei-Chiao Chang (Author)
• Format: Book
• Published: Hindawi Limited, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Rheumatoid arthritis (RA), a chronic inflammatory disease usually occurring in synovial tissues and joints, is highly associated with genetic and environmental factors. ORAI1, a gene related to cellular immune system, has been shown to be involved in the pathogenesis of chronic inflammatory diseases...