Exogenous Pancreatic Kallikrein Improves Diabetic Cardiomyopathy in Streptozotocin-Induced Diabetes

• Main Authors: Meng Wu (Author), Yeping Yang (Author), Meng Wang (Author), Fangfang Zeng (Author), Qin Li (Author), Wenjuan Liu (Author), Shizhe Guo (Author), Min He (Author), Yi Wang (Author), Jie Huang (Author), Linuo Zhou (Author), Yiming Li (Author), Ji Hu (Author), Wei Gong (Author), Zhaoyun Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aims: To evaluate the protective effects of exogenous pancreatic kallikrein (PKK) treatment on diabetic cardiomyopathy (DCM) and explore the underlying mechanisms.Methods and Results: Streptozotocin (STZ)-induced diabetic rats, a type 1 diabetic model, were treated with either PKK or saline for 12 w...