Fluconazole nanoparticles prepared by antisolvent precipitation technique: Physicochemical, in vitro, ex vivo and in vivo ocular evaluation

• मुख्य लेखकों: Amal El Sayeh F. Abou El Ela (लेखक), Mohamed Abbas Ibrahim (लेखक), Yara Alqahtani (लेखक), Aliyah Almomen (लेखक), Fadilah Sfouq Aleanizy (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2021-06-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The goal of this research was to prepare and characterize nanonized particles of the antifungal drug, fluconazole (FLZ) using antisolvent precipitation nanonization technique to improve its ocular permeation. The impact of various concentrations of different stabilizers, namely Pluronic F-127 (PL F...