AT-406, an IAP Inhibitor, Activates Apoptosis and Induces Radiosensitization of Normoxic and Hypoxic Cervical Cancer Cells

• Main Authors: Jing Lu (Author), Qin Qin (Author), Liang-Liang Zhan (Author), Jia Liu (Author), Hong-Cheng Zhu (Author), Xi Yang (Author), Chi Zhang (Author), Li-Ping Xu (Author), Zhe-Ming Liu (Author), Di Wang (Author), He-Qing Cui (Author), Ciu-Ciu Meng (Author), Jing Cai (Author), Hong-Yan Cheng (Author), Xin-Chen Sun (Author)
• Format: Book
• Published: Elsevier, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

IAP antagonists increased the antitumor efficacy of X-irradiation in some types of cancers, but their effects on hypoxic cancer cells remain unclarified. We aims to investigate the radiosensitizing effect of an IAP inhibitor AT-406 on cervical cancer cell lines under both normoxia and hypoxia condit...