Evaluation of the Pharmacological Profile of Ramosetron, a Novel Therapeutic Agent for Irritable Bowel Syndrome

• المؤلفون الرئيسيون: Takuya Hirata (مؤلف), Yoshihiro Keto (مؤلف), Toshiyuki Funatsu (مؤلف), Shinobu Akuzawa (مؤلف), Masao Sasamata (مؤلف)
• التنسيق: كتاب
• منشور في: Elsevier, 2007-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

We examined the pharmacological profile of ramosetron, a 5-HT3-receptor antagonist for irritable bowel syndrome with diarrhea, comparing it with those of other 5-HT3-receptor antagonists, alosetron and cilansetron, and the anti-diarrheal agent loperamide. Ramosetron showed high affinity for cloned h...