Evaluation of the Pharmacological Profile of Ramosetron, a Novel Therapeutic Agent for Irritable Bowel Syndrome

• मुख्य लेखकों: Takuya Hirata (लेखक), Yoshihiro Keto (लेखक), Toshiyuki Funatsu (लेखक), Shinobu Akuzawa (लेखक), Masao Sasamata (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2007-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

We examined the pharmacological profile of ramosetron, a 5-HT3-receptor antagonist for irritable bowel syndrome with diarrhea, comparing it with those of other 5-HT3-receptor antagonists, alosetron and cilansetron, and the anti-diarrheal agent loperamide. Ramosetron showed high affinity for cloned h...