Selection of Suitable Prodrug Candidates for in vivo Studies via in vitro Studies; The Correlation of Prodrug Stability in Between Cell Culture Homogenates and Human Tissue Homogenates
Purpose. To determine the correlations/discrepancies of drug stabilities between in the homogenates of human culture cells and of human tissues. Methods. Amino acid/dipeptide monoester prodrugs of floxuridine were chosen as the model drugs. The stabilities (half-lives) of floxuridine prodrugs in hum...
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| Main Authors: | , |
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| Format: | Book |
| Published: |
Frontiers Media S.A.,
2012-07-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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Internet
Connect to this object online.3rd Floor Main Library
| Call Number: |
A1234.567 |
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| Copy 1 | Available |