A Novel Src Kinase Inhibitor, M475271, Inhibits VEGF-Induced Human Umbilical Vein Endothelial Cell Proliferation and Migration

• Main Authors: Nermin Ali (Author), Masanori Yoshizumi (Author), Yoshiko Fujita (Author), Yuki Izawa (Author), Yasuhisa Kanematsu (Author), Keisuke Ishizawa (Author), Koichiro Tsuchiya (Author), Seiji Yano (Author), Saburo Sone (Author), Toshiaki Tamaki (Author)
• Format: Book
• Published: Elsevier, 2005-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Vascular endothelial growth factor (VEGF) was reported to be a potent proangiogenic factor that plays a pivotal role in both physiological and pathological angiogenesis. M475271, 4-quinazolinamine, N-(2-chloro-5-methoxyphenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl) methoxy]-(9Cl), is a new anilinoqui...