Glomerular Endothelial Cells as Instigators of Glomerular Sclerotic Diseases

• Main Authors: Marloes Sol (Author), Jan A. A. M. Kamps (Author), Jacob van den Born (Author), Marius C. van den Heuvel (Author), Johan van der Vlag (Author), Guido Krenning (Author), Jan-Luuk Hillebrands (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Glomerular endothelial cell (GEnC) dysfunction is important in the pathogenesis of glomerular sclerotic diseases, including Focal Segmental Glomerulosclerosis (FSGS) and overt diabetic nephropathy (DN). GEnCs form the first cellular barrier in direct contact with cells and factors circulating in the...