Effect of experimental gestational diabetes and administration of glibenclamide on mRNA level of NLRP3-inflammasome and distribution of NLRP3+-cells in mesenteric lymph nodes in progeny

• Main Authors: Т. М. Prozorova (Author), V. A. Kamyshna (Author), О. М. Kamyshnyi (Author)
• Formato: Livro
• Publicado em: Zaporozhye State Medical University, 2017-08-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

A number of dysfunctions of congenital and adaptive components of the immune system are observed in progeny of rats with experimental gestational diabetes (EGD). The key link in pathogenesis of EGD and other diseases is the activation of NLRP3-inflammasome. Therefore, it is an attractive target for...