The glutamate receptor GluK2 contributes to the regulation of glucose homeostasis and its deterioration during aging

• Main Authors: Myriam Abarkan (Author), Julien Gaitan (Author), Fanny Lebreton (Author), Romain Perrier (Author), Manon Jaffredo (Author), Christophe Mulle (Author), Christophe Magnan (Author), Matthieu Raoux (Author), Jochen Lang (Author)
• Formato: Livro
• Publicado em: Elsevier, 2019-12-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Objective: Islets secrete neurotransmitters including glutamate which participate in fine regulation of islet function. The excitatory ionotropic glutamate receptor GluK2 of the kainate receptor family is widely expressed in brain and also found in islets, mainly in α and γ cells. α cells co-release...