Extracellular Vesicle Delivery of Neferine for the Attenuation of Neurodegenerative Disease Proteins and Motor Deficit in an Alzheimer's Disease Mouse Model

• Main Authors: Bin Tang (Author), Wu Zeng (Author), Lin Lin Song (Author), Hui Miao Wang (Author), Li Qun Qu (Author), Hang Hong Lo (Author), Lu Yu (Author), An Guo Wu (Author), Vincent Kam Wai Wong (Author), Betty Yuen Kwan Law (Author)
• Format: Book
• Published: MDPI AG, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Exosomes are nano-extracellular vesicles with diameters ranging from 30 to 150 nm, which are secreted by the cell. With their role in drug cargo loading, exosomes have been applied to carry compounds across the blood-brain barrier in order to target the central nervous system (CNS). In this study, h...