Molecular biology of human epidermal receptors, signaling pathways and targeted therapy against cancers: new evidences and old challenges

ABSTRACT Human epidermal receptors (HER1/2/3/4) belong to the class of receptor-type tyrosine kinases. After binding a ligand, dimerization, it will ocurr activation of intracellular kinases after two-dimensional and cytoplasmic tail reciprocal transphosphorylation. This transphosphorylation recruit...

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Main Authors: Paulo Michel Pinheiro Ferreira (Author), Cláudia Pessoa (Author)
Format: Book
Published: Universidade de São Paulo, 2017-07-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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