Discovery of new VEGFR-2 inhibitors based on bis([1, 2, 4]triazolo)[4,3-a:3',4'-c]quinoxaline derivatives as anticancer agents and apoptosis inducers

• Main Authors: Nawaf A. Alsaif (Author), Mohammed S. Taghour (Author), Mohammed M. Alanazi (Author), Ahmad J. Obaidullah (Author), Abdulrahman A. Al-Mehizia (Author), Manal M. Alanazi (Author), Saleh Aldawas (Author), Alaa Elwan (Author), Hazem Elkady (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Herein, a new wave of bis([1, 2, 4]triazolo)[4,3-a:3',4'-c]quinoxaline derivatives have been successfully designed and synthesised. The synthesised derivatives were biologically investigated for their cytotoxic activities against HepG2 and MCF-7. Also, the tested compounds were further exa...