Discovery of new VEGFR-2 inhibitors based on bis([1, 2, 4]triazolo)[4,3-a:3',4'-c]quinoxaline derivatives as anticancer agents and apoptosis inducers

• Автори: Nawaf A. Alsaif (Автор), Mohammed S. Taghour (Автор), Mohammed M. Alanazi (Автор), Ahmad J. Obaidullah (Автор), Abdulrahman A. Al-Mehizia (Автор), Manal M. Alanazi (Автор), Saleh Aldawas (Автор), Alaa Elwan (Автор), Hazem Elkady (Автор)
• Формат: Книга
• Опубліковано: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Herein, a new wave of bis([1, 2, 4]triazolo)[4,3-a:3',4'-c]quinoxaline derivatives have been successfully designed and synthesised. The synthesised derivatives were biologically investigated for their cytotoxic activities against HepG2 and MCF-7. Also, the tested compounds were further exa...