Lipidomics reveals carnitine palmitoyltransferase 1C protects cancer cells from lipotoxicity and senescence

• প্রধান লেখক: Huizhen Zhang (লেখক), Yongtao Wang (লেখক), Lihuan Guan (লেখক), Yixin Chen (লেখক), Panpan Chen (লেখক), Jiahong Sun (লেখক), Frank J. Gonzalez (লেখক), Min Huang (লেখক), Huichang Bi (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2021-06-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Lipotoxicity, caused by intracellular lipid accumulation, accelerates the degenerative process of cellular senescence, which has implications in cancer development and therapy. Previously, carnitine palmitoyltransferase 1C (CPT1C), a mitochondrial enzyme that catalyzes carnitinylation of fatty acids...