Chronic cholestasis detection by a novel tool: automated analysis of cytokeratin 7-stained liver specimens

• Main Authors: Nelli Sjöblom (Author), Sonja Boyd (Author), Anniina Manninen (Author), Anna Knuuttila (Author), Sami Blom (Author), Martti Färkkilä (Author), Johanna Arola (Author)
• Format: Book
• Published: BMC, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The objective was to build a novel method for automated image analysis to locate and quantify the number of cytokeratin 7 (K7)-positive hepatocytes reflecting cholestasis by applying deep learning neural networks (AI model) in a cohort of 210 liver specimens. We aimed to study th...