Carbon Monoxide Inhibits Tenascin-C Mediated Inflammation via IL-10 Expression in a Septic Mouse Model

• Main Authors: Md. Jamal Uddin (Author), Chun-shi Li (Author), Yeonsoo Joe (Author), Yingqing Chen (Author), Qinggao Zhang (Author), Stefan W. Ryter (Author), Hun Taeg Chung (Author)
• Format: Book
• Published: Hindawi Limited, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tenascin-C (TN-C), an extracellular matrix (ECM) glycoprotein, is specifically induced upon tissue injury and infection and during septic conditions. Carbon monoxide (CO) gas is known to exert various anti-inflammatory effects in various inflammatory diseases. However, the mechanisms underlying the...