Pulmonary delivery of influenza vaccine formulations in cotton rats: site of deposition plays a minor role in the protective efficacy against clinical isolate of H1N1pdm virus

• मुख्य लेखकों: Yoshita Bhide (लेखक), Jasmine Tomar (लेखक), Wei Dong (लेखक), Jacqueline de Vries-Idema (लेखक), Henderik W. Frijlink (लेखक), Anke Huckriede (लेखक), Wouter L. J. Hinrichs (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Administration of influenza vaccines to the lungs could be an attractive alternative to conventional parenteral administration. In this study, we investigated the deposition site of pulmonary delivered liquid and powder influenza vaccine formulations and its relation to their immunogenicity and prot...